| Part I | 1787-1794 | |
| 1 | The Ohio Country | p. 3 |
| 2 | Forth to the Wilderness | p. 35 |
| 3 | Difficult Times | p. 67 |
| 4 | Havoc | p. 91 |
| Part II | 1795-1814 | |
| 5 | A New Era Commences | p. 121 |
| 6 | The Burr Conspiracy | p. 151 |
| 7 | Adversities Aplenty | p. 165 |
| Part III | 1815-1863 | |
| 8 | The Cause of Learning | p. 195 |
| 9 | The Travelers | p. 221 |
| 10 | Journey's End | p. 241 |
| Acknowledgments | p. 259 | |
| Notes | p. 265 | |
| Bibliography | p. 301 | |
| Index | p. 315 |